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He & She MD review: a named pharmacy, and a headline price that is a year paid up front

Two prices matter at He & She MD: $199 a month for compounded semaglutide if you want the ability to stop after a month. The other is $1,188 charged once up front, which is what the $99 on its banner actually means. Tirzepatide is $299 month to month, and its cheapest rung is $1,908 for the year. The good habit here is that the amount actually charged is printed beside every term, billing is monthly rather than every four weeks, and the dispensing pharmacy is named with a street address and a phone number. The gap: no milligram figure is published against any GLP-1 plan, so the dose your money buys is never stated. Brand pens have their own pages, but the plan prices above are for a compounded medicine a clinician has to prescribe first.

3.4/ 5 — our verdict on He & She MD as a GLP-1 telehealth option

How we fund our reviews

Metabolic Pantry runs on reader support. When a product we rate links out to a seller, that link may be an affiliate link — buy through it and we may earn a commission at no extra cost to you. What we write about a product is the same either way — the 0–5 ratings and the candid write-ups, including on the products we earn nothing from, are settled on price, formula, and honesty. Read the full breakdown in our funding disclosure.

FTC disclosure. Metabolic Pantry has an affiliate partnership with He & She MD and may earn a commission, at no extra cost to you, if you start a plan through our link. We reached this verdict knowing that, and every watch-out below is published in the same detail as the things we like. Full detail in our funding disclosure.

Read this first. He & She MD is a prescription medical service, not a “natural GLP-1” supplement. Its GLP-1 medication is compounded semaglutide or tirzepatide — not an FDA-approved finished product like Wegovy or Zepbound. A real GLP-1 medication is far more powerful than anything on our supplement shelf, and it carries side effects, screening requirements and cost to match. Treat this as a medical decision to make with a clinician, not an impulse buy.

What we like

  • It names the pharmacy that dispenses. Its FAQ gives F&F Pharmacies Inc, doing business as Jungle Jim's Pharmacy, 5484 Dixie Highway, Fairfield, OH 45014, with a phone number. A name, a street address and a number is a disclosure you can act on, and most prescription telehealth in this ranking stops at 'a licensed US pharmacy'. Two qualifiers: that facility is one other storefronts also name, so it identifies who dispenses rather than anything exclusive here, and no 503A or 503B classification is stated for it anywhere on the site.
  • Its GLP-1 plan page publishes the amount actually charged beside every term, not just a monthly equivalent: compounded semaglutide at $199 a month billed monthly, $447 every three months, $834 every six and $1,188 once for the year; compounded tirzepatide at $299 monthly, $627, $1,194 and $1,908. A genuine month-to-month rung exists on both, so no prepay is required to start.
  • Billing is monthly, not every four weeks — twelve charges a year rather than thirteen — and medication if prescribed, injection supplies, shipping, provider support and unlimited messaging are inside the plan price with no membership fee. You are only charged if a clinician prescribes.
  • It sells a real brand-name route beside the compounded line: Ozempic, Wegovy, Zepbound and Mounjaro each have their own page, so the FDA-approved option is genuinely on the menu rather than implied.

Watch-outs

  • Every headline the site publishes is the twelve-month prepaid rate. The banner reads 'Injectable Semaglutide $199/month from just $99/month', and reaching $99 means $1,188 charged once, up front. The rate you pay if you want the ability to stop after a month is $199 — a two-fold gap between the advertised number and the flexible one.
  • $139 and $99 are SEMAGLUTIDE rates, not tirzepatide. The site's own footnotes mark one promotion 'only applies to Tirzepatide' and the other 'only applies to Semaglutide'. Tirzepatide's month-to-month rate is $299 and its cheapest rung is $1,908 for a year. A publisher who skims the banners will file the wrong molecule's price.
  • The site makes two different claims about who regulates its pharmacies. A disclaimer says medication is 'produced in USP-compliant, state-regulated pharmacies but not reviewed by the FDA for safety, efficacy, or quality'. A feature block on the same homepage is headed 'FDA-regulated pharmacies'. Both are live on the page you land on.
  • Publishes no corporate entity for the storefront itself — though its clinical provider (Wasef Health, PC c/o Michael Wasef MD) and its CMO (Dr. Ozita Cooper, MD) are both named — and the address it gives is a PO Box, on a site that will not ship to PO Boxes. Its own FAQ says the pharmacy it names maintains a license in 44 US states, holds none in California, Nevada, New Jersey, North Carolina, Texas, Massachusetts, Mississippi, New Hampshire, West Virginia or Delaware, and “cannot dispense sterile compounds” — while the same FAQ says GLP-1s ship everywhere except Louisiana. Injectable GLP-1s are sterile compounds, and the site never says which of its two pharmacies covers the gap.
  • No milligram figure is published against any GLP-1 plan, so the dose the price buys is not stated anywhere. Its longevity and hormone lines go further: estradiol, progesterone, testosterone, sermorelin, glutathione and MOTS-c each have a page and none carries a price at all.

He & She MD vs a ‘natural GLP-1’ supplement

A supplement and a prescription GLP-1 are not two versions of the same thing. A probiotic or a fiber nudges your own GLP-1 modestly; a prescribed GLP-1 acts on the receptor at a strength no capsule reaches. He & She MD is in the second lane, with hormone, testosterone, hair and longevity lines that are a third category again. If you are comparing its numbers with anything on our shelf, compare against $199 and $299 — the month-to-month rungs — rather than the prepaid figures its banners lead with. Read our supplements vs GLP-1 drugs breakdown before you decide which lane you are in.

Not ready for a prescription? Our #1 supplement pick

If you want to start with a supplement — no clinician visit, no drug side effects, no compounded sourcing to vet — the best-value option we have rated is CoreAge Rx GLP-1 Support: a transparent, clinician-backed daily probiotic with three live strains plus prebiotic fiber, from $23.83 / bottle, no prescription required. It remains our overall #1 pick across the whole supplement shelf. He & She MD is the step you take when a supplement isn’t enough — not a replacement for one.

Check CoreAge GLP-1 Support price4.5 / 5 · our top supplement

The bottom line

He & She MD publishes more than most prescription telehealth we measure this shelf against: a full four-term ladder for both molecules before any intake, the amount actually charged printed beside each term, and the dispensing pharmacy named with a street address and a phone number. What it takes back is the headline. Every banner figure is a year paid up front, and the rate that lets you stop after a month is roughly double it. Its own FAQ then sets the pharmacy it names — licensed in 44 states, and unable to dispense sterile compounds — against a shipping promise that covers every state but Louisiana, and never says which of its two pharmacies closes that gap. Budget against $199 semaglutide and $299 tirzepatide, and treat every figure below those as the price of committing a year. We rate it 3.4 out of 5.

This page is informational and not medical advice. GLP-1 medications are prescription drugs; whether one is right for you is a decision for a licensed clinician who knows your history. Compounded medications are not FDA-approved finished products, and quality can vary by pharmacy. Every figure on this page was read off He & She MD’s own published pages, price feeds and policy documents in August 2026; confirm current pricing, sourcing, state availability and terms with He & She MD before starting, and talk to your own doctor first. We also screened He & She MD against the FDA’s own warning-letter index, with a known positive control returned in the same pass, and found no FDA warning letter against this company.

He & She MD: the questions people ask

How much does He & She MD cost?
He & She MD publishes compounded semaglutide at $199/mo month to month. That is the figure we read off its own pages and verified on August 14, 2026; prices in this category move, so check the current rate before you pay.
What is the biggest catch with He & She MD?
Every headline the site publishes is the twelve-month prepaid rate. The banner reads 'Injectable Semaglutide $199/month from just $99/month', and reaching $99 means $1,188 charged once, up front. The rate you pay if you want the ability to stop after a month is $199 — a two-fold gap between the advertised number and the flexible one.
What does He & She MD do well?
It names the pharmacy that dispenses. Its FAQ gives F&F Pharmacies Inc, doing business as Jungle Jim's Pharmacy, 5484 Dixie Highway, Fairfield, OH 45014, with a phone number. A name, a street address and a number is a disclosure you can act on, and most prescription telehealth in this ranking stops at 'a licensed US pharmacy'. Two qualifiers: that facility is one other storefronts also name, so it identifies who dispenses rather than anything exclusive here, and no 503A or 503B classification is stated for it anywhere on the site.
What do we rate He & She MD?
3.4 out of 5, on the same rubric as every other program on this site: what the seller publishes about price and terms, what it discloses about who dispenses, and whether its own pages agree with each other. The score has no input for whether a company pays us.

Answers reflect what He & She MD published when we checked, and the FDA warning-letter position is drawn from the FDA’s searchable database.

The other programs we have reviewed

Every prescription GLP-1 program this site has actually written up, with the price each one publishes and the terms attached to it. A program whose price we cannot state in one honest line is listed here without a number rather than with a flattering one.